Investigation of Intraocular Lenses Surface Roughness by Atomic Force Microscopy

The aim of this study was to evaluate the surface roughness of intraocular lenses (IOLs) generated by the manufacturing process and to determine the roughness parameters of 3D surface using atomic force microscopy (AFM). Intraocular lenses commercially available from a single manufacturer: Pharmacia & Upjohn Co. were investigated. Three intraocular lenses, model 911A CeeOn Edge, were analyzed on different areas of the posterior optic surface. For imaging surface roughness of intraocular lenses on nanometer scale we employed atomic force microscopy in contact mode with ambient air. Three parameters obtained by atomic force microscopy (Sa, Sq and Sz) were used in evaluation of intraocular lenses surface roughness. The parameters of surface roughness are an auxiliary index of biocompatibility and generates useful information about the material surface quality. The information generated in study may assist researchers in choosing, designing and manufacturing of intraocular lenses with optimal performance characteristics.